Contains urea and 10% l-arginine. Podiatrist recommended. Fast-acting formula. Strongest formula without a prescription. Soothes & smoothes rough, cracked skin. Gently softens thick skin & calluses. Why the heels, toes and soles of your feet require a special kind of cream. The heel, toes and bottom (sole) of feet are extremely brittle and prone to cracks, sores, and calluses when dry. This is because in these areas of the foot the outer layers of skin can be up to 40 times thicker, and difficult to hydrate. DiabetiDerm Heel & Toe Cream gently penetrates this extra-thick skin and delivers much needed moisturizers, softening and healing agents. Maximum relief of dry, rough & cracked skin. Made in the USA.